TH 257

CAS No. 2244678-29-1

TH 257( —— )

Catalog No. M20839 CAS No. 2244678-29-1

TH 257 is a Potent and selective allosteric LIMK 1/2 inhibitor(LIMK1 and LIMK2 IC50 of 84 nM and 39 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 53 In Stock
10MG 84 In Stock
25MG 168 In Stock
50MG 292 In Stock
100MG 472 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    TH 257
  • Note
    Research use only, not for human use.
  • Brief Description
    TH 257 is a Potent and selective allosteric LIMK 1/2 inhibitor(LIMK1 and LIMK2 IC50 of 84 nM and 39 nM).
  • Description
    TH 257 is a Potent and selective allosteric LIMK 1/2 inhibitor(LIMK1 and LIMK2 IC50 of 84 nM and 39 nM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    LIM Kinase (LIMK)
  • Recptor
    LIMK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2244678-29-1
  • Formula Weight
    422.5
  • Molecular Formula
    C24H26N2O3S?
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:250 mg/mL?(591.66 mM)
  • SMILES
    CCCCN(Cc1ccccc1)C(=O)c1ccc(S(=O)(=O)Nc2ccccc2)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fabrizio M . Recent advances in the rational design and development of LIM kinase inhibitors are not enough to enter clinical trials[J]. European Journal of Medicinal Chemistry 2018:S0223523418305075-.
molnova catalog
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